Projects / Bulgarian
PhD Students Projects
| Project Title | Year | Principal Investigator (PI)/Co-Principal Investigator (coPI) | Organisation |
| Expression analysis of molecular markers in circulating tumour cells (CTC) from peripheral blood in Bulgarian patients with metastasized breast carcinoma | 2013-2014 | Daniela Dacheva (MSc), PhD student |
Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, MU-Sofia |
| Expression profiling of miRNAs in blood plasma and urine of prostate cancer patients | 2013-2014 | D. Kachakova (MSc), PhD student | Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, MU-Sofia |
| Connection between neurocognitive disruptions in patients with BAR type-1 and genetic polymorphisms in DISC1 | 2013-2014 | Mladen Penchev (MD), PhD student | Department Psychiatry, MU-Sofia |
| Genetic aspects of the non-syndromic loss of hearing - Connexin 26, 30, and 31 | 2013-2014 | Iglika Stancheva (MD), PhD student | Department of ORL, University Hospital "Tzaritza Yoanna", MU-Sofia |
| Association study of polymorphic variants in leading candidate - genes from GWAS in patients with coronary artery disease in Bulgarian population | 2013-2014 | R. Tzveova (MSc), PhD student | Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, MU-Sofia |
| Molecular and genetic factors in angiogenesis of laryngeal squamous cell carcinoma | 2013-2014 | T. Popov, MD, PhD student | Department of ORL, University Hospital "Tzaritza Yoanna", MU-Sofia |
| Mutation screening of LRRK2 in Bulgarian patients with Parkinson`s Disease | 2013-2014 | Kalina Mihova (MSc), PhD student |
Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, MU-Sofia |
| Methodology of isolation and keeping of tumour tissues for the detection of prognostic and predictive factors in mammary gland carcinoma | 2013-2014 | Mariela Vasileva (MD), PhD student | Department of Surgery, ÌÓ-Ñîôèÿ |
| Introducing a mutational analysis of SOX2 in Bulgarian patients with congenital hyposomatotropism and/ or vision anomalies | 2012-2013 | A. Aroyu, MD, PhD student | Department of Pediatry, MU - Sofia |
| Genetic aspects of nonsyndromic deafness - connexin 26 and 30 | 2012-2013 | I. Stancheva, MD, PhD student | Department of ORL, University Hospital "Tzaritza Yoanna", MU-Sofia |
| Expression levels of miRNAs in blood and synovial fluid as potential biomarkers for diagnostics and prognosis in rheumatoid arthritis | 2012-2013 | R. Shumnalieva, MD, PhD student | Department of Internal Medicine, MU - Sofia |
| Molecular and genetic basis of angiogenesis in squamous cell carcinoma of the larynx | 2012-2013 | T. Popov, MD, PhD student | Department of ORL, University Hospital "Tzaritza Yoanna", MU-Sofia |
| Expression profiling of miRNAs in prostate tissues and plasma of Bulgarian prostate cancer patients | 2012-2013 | D. Kachakova (MSc), PhD student | Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, MU-Sofia |
| Impact of genetic factors on the therapy with indirect anticoagulants of Bulgarian patients with cardiovascular diseases | 2012-2013 | R. Tzveova (MSc), PhD student | Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, MU-Sofia |
| Analysis of large genomic deletions, insertions and rearrangements in BRCA1 and BRCA2 ãgenes in Bulgarian patients with triple negative breast cancer | 2012-2013 | R. Dodova (MSc), PhD student | Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, MU-Sofia |
| Expression analysis of CAIX, MMP-9 and TGF-β2 genes and their application as prognostic markers in malignant glial tumours | 2012-2013 | G. Stancheva (MSc), PhD student | Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, MU-Sofia |
| Promoter hypermethylation in laryngeal carcinogenesis | 2011-2012 | S. Jordanov, MD, PhD student | Department of ORL, University Hospital "Tzaritza Yoanna", MU-Sofia |
| Genetic analysis of mutations in exon 11 of BRCA2 gene in Bulgarian patients with hereditary breast cancer | 2011-2012 | R. Dodova (MSc), PhD student | Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, MU-Sofia |
| Association study of candidate genes for suicidal behaviour in patients with various psychiatric disorders | 2011-2012 | Turan Asan, MD, PhD student |
Department of Psychiatry, MU - Sofia |
| Analysis of mutations in IDH1, IDH2 and TP53 genes and 1p/19q deletions in Bulgarian patients with malignant glial tumours | 2011-2012 | G. Stancheva (MSc), PhD student | Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, MU-Sofia |
| Molecular genetic analysis of SLC2A1 gene and phenotype-genotype correlations in patients with absanse epilepsy of early development | 2011-2012 | D. Kancheva (MSc), PhD student | Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, MU-Sofia |
| Association study of polymorphic variants in locus 11ð15 and their role in prostate carcinogenesis | 2011-2012 | D. Kachakova (MSc), PhD student | Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, MU-Sofia |
| Analysis of polymorphisms in low-penetrance genes associated with high risk of breast cancer | 2010-2011 | R. Dodova (MSc), PhD student | Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, MU-Sofia |
| Genetic markers with prognostic value in high-grade gliomas | 2010-2011 | G. Stancheva (MSc), PhD student | Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, MU-Sofia |
| Determination of mutation frequencies in MSH6 gene between patients with endometrial carcinoma which biopsycal materials show inactivating mutations in KRAS gene | 2009-2010 | D. Konstantinova (MSc), PhD student | Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, MU-Sofia |
| Association study of polymorphic variants in regulatory genes of androgen biosynthesis (CYP1B1, CYP19 SRD5A2) with increased risk for development of prostate cancer in Bulgaria | 2008-2009 | E. Popov, MD, PhD Student | University Hospital "Aleksandrovska", Department of Urology |
| Molecular-genetic analysis of SCN1A gene and phenotype- genotype correlations in patients with generalized epilepsy with febrile seizures plus (GEFS+) | 2007-2008 | I. Jordanova (MSc), PhD student | Department of Obstetrics and Gynaecology, Medical Faculty, Medical University-Sofia |
| Association study of the role of I157T polymorphism in CHEK2 gene for developing of colorectal and endometrial carcinoma in Bulgarian patients | 2007-2008 | D. Konstantinova (MSc), PhD student | Medical Chemistry and Biochemistry Department, Medical Faculty, Medical University-Sofia |
| Prognostic value of timidilat synthase expression in patients with colorectal carcinoma | 2006-2007 | N. Nedialkov , MD, PhD student | Department of Internal Medicine, Gastroenterology Clinics, University Hospital "Tzaritza Yoanna", MU-Sofia |
| Study of genetic polymorphisms 4G/5G in promoter regions of PAI-1 gene and PIA1/PIA2 from gene, coding IIIa subunit of IIb/IIIa glycoprotein receptor in patients with miocardial infarction and healthy controls in Bulgarian population | 2006-2007 | A. Nosilkov , MD, PhD student | Laboratory of Immunology, Allergology Clinics, Medical Faculty, Medical University-Sofia |
| Study of clinical molecular and genetic characteristics of nonpoliposis colorectal cancer in Bulgarian population | 2005-2006 | E. Kostadinov , MD, PhD student | Gastroenterology Clinics, University Hospital "Tzaritza Yoanna", MU-Sofia |
| 550delA CAPN3 mutation in Bulgarian patients with LGMD2A | 2003-2004 | B. Georgieva (MSc), PhD student | National Genetics Laboratory, University Hospital ``Maichin Dom`` |
| Researching promoter hypermethylation of MLH1 and MSH2 genes in connection of microsatellite instability in colorectal carcinoma | 2001-2002 | T. Kadiyska (MSc), PhD student | Medical Chemistry and Biochemistry Department, MF, MU-Sofia |
